Source: The father of stem cells

With the rapid development of regenerative medicine technology, the successful application cases of stem cells are constantly hot in the circle, and they are also favored by many high net worth people. Stem cell therapy is widely used in the treatment of many diseases, including some refractory diseases. However, little is known about the precautions before and after treatment of this emerging therapy, and the following Xiaobian takes you to quickly understand the stem cell transfusion guide. Then, what diseases can be treated by stem cells, what should be paid attention to before and after the transfusion of stem cells, and the contraindications of application will be explained in detail in this article.

Q₁ What is stem cell transfusion?

Stem cell transfusion also refers to "stem cell transplantation", which is a part of cell biological therapy, mainly through in vitro identification, separation and purification of cells in various tissues of the human body, to obtain stem cells required for clinical application, and then through intravenous transfusion or intervention and other methods for transfusion intervention.

Stem cells move around damaged organs and tissues, play a role in promoting cell repair, regeneration and renewal, and activate the body's own "self-healing function" to repair damaged cells or tissues in the body to achieve the purpose of bodily function reconstruction.

Q₂ What did the stem cells back into the human body do?

After the stem cells are transfused into the human body, they can find their own "home", and this home is a place suitable for their own survival, just like their own navigation system, always know where their home is. This is what we call "homing". After the stem cells enter the target tissue, the magical paracrine mechanism is used to make the stem cells like a "distributed power station" in the body, at the right time and in the right place, various types of factors are transported outward in a divergent mode to play the positive function of the stem cells.

Stem cells are also a type of primitive cell that can self-renew and differentiate into a variety of tissue cell types. The seed cells that may become blood, bone, skin, muscle, etc., rely on the multidirectional differentiation mechanism to further differentiate into the cells needed by the body, and then can form various organs and tissues. The main functions are as follows:

● Activate dormant cells: Dormant cells are cells that have lost cell function. Stem cells can directly activate dormant cells to restore their original physiological function.

● Replace dead cells: Stem cells can replace dead cells in time, so as to maintain the normal function of the body and delay aging.

● Repair Damaged cells: Stem cells can repair damaged cells and prevent lesions in tissues or organs.

● Regenerative active cells: Stem cells have a number of differentiation potentials, which can increase the number of functional cells and enhance cell activity.

Q₃ The way stem cells are transfused

Stem cell infusion generally uses normal saline as the carrier. At present, the main methods are intravenous infusion (the same as the usual infusion), local injection (such as joint cavity injection, ovarian spot injection) and subarachnoid injection (such as Parkinson's disease, stroke and other neurological diseases).

Q4 Efficacy and manifestation of stem cell transfusion

First stage (after 1-3 months)

Stem cells enter the body tissues and organs through the blood circulation, remove metabolic waste such as aging cells and peroxide, and activate dormant cells in the body.

Performance:

1-2 weeks: the face is rosy and shiny. Epidermal dry lines disappeared. Energy and physical strength began to improve. The sleep quality was improved and the time to fall asleep was significantly shortened.

3-4 weeks: physical strength is significantly improved, and the anti-fatigue effect is obvious. The anti-aging effect of skin is obvious. Richer skin

Elasticity and fine wrinkles are significantly reduced. The improvement of autonomic nerve regulation, such as transient irritability, night sweating, sometimes palpitation, and poor sleep, appears individually; And itchy skin, regrowth like an ant crawling around.

Second stage (3-6 months)

Stem cells activate dormant cells in the body, the rate of cell differentiation reaches the growth stage level, comprehensively repair damaged, aging and diseased cells, and replenish fresh cells to restore tissues and organs to the most dynamic state.

Performance: After 3 months, the repair performance of various organs, wound healing accelerated, and the color spots faded significantly. Nervous system: Improves memory; Increased mobility of limbs. Reproduce hair color, promote hair growth, some white hair to black hair.

Stage 3 (after 6-9 months)

Stem cells play a full role in the body, and the damaged cells in the human body are well targeted repair and regeneration. Cells in the body are newly differentiated, cell vitality is strong, and the human body recovers and maintains a young and healthy state. At the same time, it can adjust the internal environment of disease risk genes, make risk genes in a relatively static state, and prevent the occurrence of diseases.

Manifestations: Some of the symptoms of age-related diseases have improved significantly, or even disappeared. Rebuild muscle, remove fat, rebuild body shape, lower LDL cholesterol and triglyceride triphosphate, normalize blood pressure, and look completely youthful.

Q₅ What are the contraindications of stem cell therapy?

AIDS, hepatitis B active period, syphilis virus positive; People who are highly allergic or have a history of severe allergies; Malignant tumors of patients with dysfunction of heart, liver, lung, kidney and other important organs are being treated with radiotherapy and chemotherapy; The treatment period of sudden disease should be prohibited, and the condition is stable for 2-3 months. Coagulation dysfunction; Mental illness; Pregnant women; Systemic infection or severe local infection. (Note: The stem cell infusion must be carried out after a strict physical examination and expert evaluation)

Q₆ Common manifestations of stem cell retransfusion

Fever occurs after the stem cell transfusion, generally within 24 hours will appear about 38°C, return to normal within 3 days, if the fever does not return, you need medical observation.

Stem-cell transfusions were accompanied by improved mental performance, fatigue with a little lethargy, and slight muscle soreness.

According to the data analysis, feeling tired will be slightly more, because the repair and activation work in the body is being carried out nervously, just like the people who feel tired with a viral cold, because the immune system in the body is being mobilized to fight with the invading virus and bacteria, so feeling tired is a normal repair response.

Q₇ Precautions for transfusing stem cells

Before the stem cell transfusion, professional physical examination is required, including basic physical examination, four infectious diseases, liver and kidney function examination, tumor marker detection, etc., and professional doctors evaluate whether it meets the stem cell treatment standards.

Back one day

Eat a light, easy to digest diet, avoid spicy, stimulating food and seafood. Avoid strenuous exercise, go to bed early at night, and get enough sleep.

Tips after losing

1. Diet: drink more warm water to clear the intestine and moisten the stomach, more vinegar and less salt, often eat seasonal fruits, or mild fruits with health effects; Eat less and more meals, and it is best to drink a small amount of soup before meals to ensure that the stomach is warm and moist, and contribute to the health of the stomach.

2. Work and rest: keep enough sleep, don't stay up late, go to bed early and get up early, exercise properly, work and rest regularly, ensure sleep while it is best to fall asleep before 11 o 'clock every night, 15 days should not be overworked, engaged in excessive physical and mental labor; Nap time should not be too long to half an hour is appropriate, more gentle and gentle physical activities (such as walking, tai chi, aerobic dance, etc.) to develop a good work and rest habits.

3. State of mind: keep a happy mood, listen to more music, within a week should maintain a good mood, guard against arrogance and impetuous, open-minded, trouble should not be excited, maintain a stable and harmonious state of mind, make yourself more positive and healthy from inside and outside, so that the body tends to the best state.

4. Don 'ts:

① Tobacco, alcohol and other irritating items to the human body;

② Strong tea, strong coffee and other stimulating drinks;

③ Spicy stimulating food, after health care within a week to prohibit the consumption of spicy food, two weeks after you can eat ginger garlic and other good for the human body spicy spices, try to fast pepper.

5. Note:

In order to avoid the needle eye hardening, bruising, skin bruising. After health care, it is forbidden to slap the eye of the needle, press, rub, prohibit needle handbag, arm droop, lift shoes, do physical housework, driving motion amplitude is too large. If there is indentation, bruising, and skin bruising around the needle eye, there is no need to stress, and this symptom can disappear automatically in one week and two weeks in severe cases.

Try not to stay up late, do not do strenuous exercise for three days after treatment, do not use sauna for one week after treatment, avoid strong sunlight exposure and mineral salt baths for one month after treatment, and try to avoid X-rays for two months (except for special health problems).

The infusion of stem cells is the same as the normal infusion, only there is slight pain at the time of puncture, and the pain is tolerable. There are very few transient fever and allergic reactions during infusion due to individual differences, but they are mild and will be relieved the next day.