In the current era of rapid advancements in medical technology, pluripotent stem cell therapy, with its tremendous potential and continuous breakthroughs, has become the core focus of the global medical field.

Recently, the field of pluripotent stem cells has witnessed a series of exciting advancements.

These two studies focus on the application of stem cell therapy in the treatment of Parkinson's disease, conducting in-depth explorations respectively on human induced pluripotent stem cells (IPscs) and human embryonic stem cells (HESCs).

Diabetes, the "sweet killer" that troubles over 400 million people worldwide, is now facing an unprecedented treatment revolution.

The core pathological feature of Parkinson's disease is the significant and progressive degeneration of dopaminergic neurons in the substantia nigra region of the brain and their projections in the striatum.

The research team has revealed that a gene recently identified as a biomarker for Alzheimer's disease (AD) - PHGDH - is actually the key cause of the disease due to its previously unknown "moonlighting role".

This study systematically reveals for the first time that "gut bacteria - bile acids - gut FXR-GLP-1 - articular cartilage axis" plays an important role in OA.

The research team built a stem cell factory with a specific culture program to achieve high-throughput production of human mitochondria, providing a new solution for the treatment of osteoarthritis.