Professor Randy Shekman (Professor of the Department of Molecular and Cell Biology at the University of California, Berkeley, former editor-in-chief of the Proceedings of the National Academy of Sciences, elected as a member of the National Academy of Sciences in 1992, and won the Nobel Prize in Physiology or Medicine in 2013) In an interview with reporters, he said: "In theory, the application of stem cell technology can treat various diseases, and it has unparalleled advantages compared with many traditional treatment methods."

Combined with the current projects of stem cells for clinical application at home and abroad, as well as the projects that have been carried out in Phase I, Phase II, and Phase III clinical trials after the IND. The following is a list of indications for stem cell clinical treatment, covering some current or potential application areas and divided into the following 11 categories.

1. nervous system disorders

Parkinson's disease: Stem cell transplantation can replace lost dopaminergic neurons.

Alzheimer's disease: Stem cell therapy helps regenerate damaged nerve cells.

Spinal cord injury: Promote spinal cord regeneration and improve motor function recovery.

Stroke: Stem cell transplants can help repair brain damage and improve neurological function.

2. blood system diseases

Leukemia: Hematopoietic stem cell transplantation has become the standard treatment for hematological cancers such as leukemia.

Aplastic anemia: Restoration of blood cell production through stem cell transplantation.

Thalassemia: Using hematopoietic stem cells to correct genetic defects.

3. immune system disorders

Systemic lupus erythematosus: Stem cell transplants help reset the patient's immune system and reduce inflammation.

Rheumatoid arthritis: Reduce joint inflammation through stem cell therapy and repair damaged tissue.

Multiple sclerosis: Stem cells have the potential to repair damage in the nervous system and slow disease progression.

4. cardiovascular disease

Myocardial infarction: Stem cell therapy can help repair damaged cardiomyocytes and improve heart function.

Heart failure: Stem cell transplants help enhance heart regeneration and relieve symptoms of heart failure.

5. ophthalmic diseases

Macular degeneration: Stem cell treatment is expected to restore retinal health and prevent or reverse blindness.

Corneal damage: Promote corneal regeneration and improve vision through stem cell transplantation.

6. skin diseases

Burns or skin damage: Stem cells can accelerate wound healing and promote healthy skin regeneration.

Scleroderma: Stem cell therapy may reduce symptoms by regulating the immune response.

7. metabolic diseases

Diabetes (type 1 diabetes): Stem cells may help create new islet cells and restore insulin secretion.

Liver disease: Repair damaged liver tissue through stem cell treatment and improve liver function.

8. Bone and joint diseases

Osteoarthritis: Stem cells can help repair cartilage tissue and slow down joint degeneration.

Non-union of fractures: Stem cell transplantation promotes bone tissue regeneration and helps fracture healing.

9. lung disease

Chronic obstructive pulmonary disease (COPD): Stem cell therapy may help repair lung tissue and improve respiratory function.

Pulmonary fibrosis: Stem cells are expected to reduce lung inflammation and fibrosis and restore some functions.

10. reproductive system diseases

Premature ovarian failure: Stem cells may help restore ovarian function and promote egg production.

Male infertility: Stem cells can be used to repair or regenerate tissues related to sperm production.

11. cancer

Solid tumors: Stem cell therapy may be combined with immunotherapy to help target cancer cells.

Tissue repair after tumor ablation: Stem cells can be used to promote the repair of damaged tissue.

The clinical application of stem cells is still expanding and in-depth research, and more fields may be confirmed to benefit from stem cell therapy in the future.